TEN PCR Services

Urinary Tract Infections 

  • 70% of UTIs caused by E. coli in the past; simple to treat.

  • Most commonly diagnosed illness in older adults.

  • Now problems with recurrent and persistent Infections.

  • Development of MDROs and Biofilms have complicated the clinical diagnosis.

  • Advanced diagnostics are needed to detect culprit pathogen that may not grow in culture due to Biofilm and also identify antibiotic resistant genes.

  • We can no longer assume our first or second-line antibiotics will work.

Upper Respiratory Infections

  • Acute respiratory infection is a major cause of morbidity and mortality in young, geriatric and immunocompromised patients.

  • Rapid antigen tests like the flu and Strep tests have created a false sense of security among patients and providers – they lack sensitivity and only focus on a single pathogen diagnosis.

  • Co-infection is HIGH in respiratory illness.

  • False negatives can lead to a delayed diagnosis and poor clinical outcomes.

Women’s Health

  • Identifying infectious pathogens that cause vaginitis, vaginosis, sexually transmitted infections, Group B Strep, yeast infections, or urinary tract infections with one swab.

  • Semiquantitative pathogen identification, antibiotic resistant gene testing and available antibiotics to treat bacterial pathogen with next day results.

  • Pregnancy Panel for obstetric patients including STI, and Group B Strep tests with next day results.

  • Advanced diagnostics used to detect culprit pathogen that may not grow in culture due to biofilms or mutations.

Wound Infections

  • 8.2M lives are affected yearly from chronic wound infection. PCR Technology can identify wound infection causing bacteria and allow treatment to be started for a chronic wound in 1 day. 

  • Chronic wounds have polymicrobial infections, sometimes with dozens of microorganisms all existing as a cooperative community. This community creates an extensive biofilm making culture unreliable.

  • 24% of diabetic foot ulcers lead to amputation due to non healing or spreading chronic infection. PCR testing could help identify and treat these infections lowering likelihood of amputation.

  • The mortality rate for leg ulcers after the first amputation has dramatically doubled from 20% to 50% in the first 3 years and to 70% after 5 years.

  • Fewer than 2% of all known bacteria can be grown routinely in the clinical microbiology laboratory. Bacteria does not have to be grown to be identified through PCR technology, making PCR testing ideal for chronic wound infection.

Antibiotic Resistance -  COMPLICATIONS OF TREATMENT

  • More than 2.8 million antibiotic-resistant infections occur in the United States each year, and more than 35,000 people die as a result. In addition, nearly 223,900 people in the United States required hospital care for C. difficile and at least 12,800 people died in 2017. https://www.cdc.gov/drugresistance/pdf/threats-report/2019-ar-threats-report-508.pdf

  • In addition, almost 250,000 people each year require hospital care for Clostridium difficile (C. difficile) infections.

  • In most of these infections, the use of antibiotics was a major contributing factor leading to the illness. At least 14,000 people die each year in the United States from C. difficile infections. Many of these infections could have been prevented. https://www.cdc.gov/drugresistance/pdf/ar-threats-2013-508.pdf

  • The use of antibiotics is the SINGLE MOST IMPORTANT FACTOR leading to antibiotic resistance around the world.

  • Antibiotics are among the MOST COMMONLY PRESCRIBED DRUG in human medicine.

  • Up to 50% of all the antibiotics prescribed for people ARE NOT NEEDED or are not optimally effective as prescribed. https://www.cdc.gov/drugresistance/pdf/ar-threats-2013-508.pdf